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One subject discontinued for personal reasons after completing the first dosing period (randomized to placebo).
The first dosing with pamidronate caused a transient drop in serum calcium that was asymptomatic and not treated.
Measurements of food consumption were initially carried out during the acclimation period (prior to the first dosing session), followed by weekly measurements throughout the entire observation period.
Subjects had to abstain from caffeine intake 2 days before the first dosing and until the end of the study and cocoa and chocolate were not allowed 24 h before the dosing day.
Plasma drug concentrations were measured in the first dosing interval.
Subjects were observed overnight and discharged 5 days after the first dosing.
Similar(26)
She took the first dose.
Dr. Mukherjee injected the first dose himself.
The first doses will be available next year, Dr. Fauci said.
The first dose resulted in a reduction in the circulation half-life of the second dose.
We have 93% coverage with the first dose by the age of two.
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