Sentence examples for the first compounds from inspiring English sources

VEGF receptor tyrosine kinase inhibitors continue to be developed, but one of the first compounds SU5416 has had minimal clinical effects.

We describe the progress achieved from the first compounds plagued with poor general kinase selectivity to compounds showing high selectivity for PI3Kα over PI3Kβ and excellent general kinase selectivity.

The first compounds (1 10) of the series proved to be H3 receptor ligands of high potency at rat synaptosomes or of high binding affinity at human H3 receptors, respectively, but of only moderate activity as inhibitors of rat kidney HMT.

The drug has attracted intense interest because it is one of the first compounds aiming to block protein clumps called amyloid from accumulating in the brains of Alzheimer's patients.

6AP and GA are therefore the first compounds to selectively inhibit the protein folding activity of the ribosome.

Sia is thus amongst the first compounds ingested by the suckling newborn and this raises the question of whether or not milk Sia serves as a nutrient.

Ephedra is just the first compound on the chopping block".

The first compound tested in clinical trials was selegiline.

They have proposed tin telluride as the first compound to show these novel properties.

To our knowledge, SPD is the first compound known to have mixed D1 antagonist antagonist properties.

In the first compound, gold is in the +1 oxidation state, and in the latter two, the +3 state.