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In this case, the factors in question may have antagonistic effects.
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For example, (#38, +5) indicates that statement number 38 appeared in position +5 for the factor in question.
For student preparation, content, group interaction, and teaching performance, we averaged the scores of items (range: 1-5) withen the scale of the factor in question for every student.
'Don't know' was included in the category 'lack of awareness' because these respondents were not aware that the factor in question was a risk factor for cancer, hence lacked awareness.
6 In most cases, prior probability can be roughly estimated by thinking about the strength of previous theoretical or empirical evidence that the factor in question is likely to modify the relative treatment effect.
One reason could be that promoter regions contain potential binding sites for the factor in question which for a variety of reasons are not represented in the ChIP data.
Clinical epidemiological studies tend to be correlative and do not necessarily indicate that the factor in question, such as NE or a noradrenergic drug, is causative in a disease process.
A given factor was scored as showing 'off-context' expression in lymphoma, if its normal tissue expression pattern was predominantly non-lymphoid; i.e. if the factor in question showed expression of 10-fold above the median in a given non-lymphoid cell or tissue type and below median expression in normal lymphoid tissues or cells.
If the selected factor is found to reverse the actions of the NELF protein by acting at the same site as the NELF protein, we can propose that the activity of the factor in question directly counters the step inhibited by NELF.
And in a few cases, the factor in question might be known to bind to only a small number of sites in the genome; this has been proposed, for example, for some ZNF TFs and Pol3 and its associated factors (Landt et al. 2012).
But even when the transcription factors in question have been identified, the problem of the energetic trade-off with pigment production and longevity will remain.
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