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The variables affecting the extraction step (namely, power of irradiation, irradiation time, extractant volume, extractant composition and number of extraction cycles) have been optimized using experimental design methodology.
In order to consider only the matrix effect and not losses during the extraction procedure, the blank extracts were spiked with known concentrations of analytes and ISs after the extraction step, followed by analysis.
The extraction step was optimised by using an experimental design.
The last stage of a puzzle that leads to the answer is called the extraction step.
The effects of various experimental parameters in the extraction step were also studied using response surface methodology.
Consequently, accuracy of environmental analyses mainly depends on the efficiency and the robustness of the extraction step.
It focused on the application of alternative and different solid supports to the extraction step of the MSPD.
The figures of merit for PARAFAC and univariate calibration procedures were evaluated under optimal conditions in the extraction step.
Finally, the addition of Mn II) was proven to be a good alternative to prevent the degradation of HSs in the extraction step.
Presence of 5% ethanol was favorable for the extraction yield, while a further decrease in pH was not, not even for the extraction step alone.
The replacement of diethyl ether was possible in the extraction step, while solvent choices were detected for potential telescoping for extraction and crystallisation steps.
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