Mark Hopwood, First Great Western managing director, said it was the "most extensive" phase of the upgrade yet.
The next, more extensive phase of the operation was due to begin on 7 January, according to a letter seen by the Press Association.
This work reveals that the new flagellum contributes to the second, most extensive, phase of basal body positioning by a combination of at least three factors: elongation, connection to the existing flagellum and base-to-tip wave propagation.
The physical methods mentioned are based on calculations with a MM force field, enabling fast energy determination through the utilisation of extensive phase space sampling [18, 19].
The second, more extensive, phase of phylogenetic analysis was carried out not only to clarify relationships within Scleractinia, but also to provide estimates of the timing of major divergences.
The Bolsena volcanic complex mainly took place in the eastern part of the Vulsini district after an extensive phase of subsidence which affected the final activity of the Paleo-Bolsena volcanic complex, responsible for a thick sequence of volcano-lacustrine deposits within the Bolsena caldera (Nappi and Valentini 2005).
Since the publication of the results of phase I dose-finding studies, an extensive phase II and III clinical study programme has been undertaken to study the clinical efficacy and tolerability of the quinazoline folate analogue raltitrexed ('Tomudex'), a novel direct and specific inhibitor of thymidylate synthase.
Overdeepened or weakly U-shaped valley segments fringing north Dartmoor document an early, extensive phase of glaciation but the most convincing landform evidence relates to more recent, valley-based glacier occupancy.
Extensive phase II investigations in the first-line setting recorded response rates of 32%to52%2% survival (median, 8 to 12 months) with 33% to 48% of patients alive at 1 year.
