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The major problem with repair of an articular cartilage injury is the extensive difference in the structure and function of regenerated, compared with normal cartilage.
The possible reasons for such a variation could be the extensive difference in the SSTR subtype profile and the nonstandardized examination conditions.
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Given the extensive differences observed at the genomic level we were interested to check different MCF-7 sublines at the transcriptome level.
This simple picture can explain the extensive differences observed between the inner and outer planets.
Transcriptional changes in response to genotoxicant exposure proved more sensitive than measurement of DNA strand breaks by the Comet assay and the extensive differences in transcription between adults and neonates emphasized the importance of life stage in toxicant testing with Daphnia.
The regulation of catalytic activity by the C-terminal domain could be mediated via differential modification, for instance phosphorylation or SUMOylation, or could be linked to the extensive differences in primary sequence between the two C-terminal domains.
The situation in Madagascar reported here, with the predominance, if not exclusive presence, of L. interrogans serogroup Canicola serovar Kuwait, confirms the extensive differences between the Leptospira strains present on the various islands in this region of the Indian Ocean, contrasting with the apparently limited variation on each island.
Nevertheless, data indicate that this effect cannot be considered sufficient to fully account for the extensive differences.
It was not expected that 100% of the genes would behave similarly because of the extensive differences in control myoblast-specific vs. control myotube-specific transcription described above.
Below, we summarize these broad patterns of plasticity, the metabolic responses to copper they imply, and the extensive differences between strains in plastic gene expression.
Despite the extensive differences in proliferative, apoptotic and growth markers, Responder and Non Responder breast tumors showed comparable reactivity for γH2AX induction in response to doxorubicin treatment.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com