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The endothelial cell injury in porphyria cutaneous tarda is one that is complement mediated as characterized in this case by the extensive degree of C5b-9 deposition within the microvasculature.

The most baffling part of the book is likely to be the extensive degree to which Erwin is able to debunk each and all of the theories he presents as possible causes for this mass extinction.

The UNI-PROT_TREMBL database was chosen for the EST and cDNA sequence analyses due to the extensive degree of annotation and output format.

Furthermore, the fact that this was seen only with HMGCR is consistent with the extensive degree to which HMGCR activity is regulated [20], and indicates that HMGCR alternative splicing is subject to additional forms of regulation.

The extensive degree of homology between the two enzymes suggested that BACE2 might also function as a β-secretase.

However, the extensive degree of polymorphism observed in these genes makes it difficult to conduct thorough population screenings.

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Intriguingly, other taxa within the genus demonstrate the opposite pattern: an extensive degree of cryptic diversity within groups of morphologically indistinguishable specimens.

Having loved and lived the album to an extensive degree, at some point last summer my relationship began to unravel.

Molecular epidemiological studies have revealed the existence of an extensive degree of diversity of HIV-1 isolates [1].

A striking exception to the "rule" of deep layer predominance is posed by the laminar activity distribution in the retrosplenial cortex (RSC) which stands out from the rest of the neocortex by its comparably extensive degree of superficial layer activation (Fig.  5).

The collected images produced an extensive degree of yellow hot- spots (co-localization) and quantitative analysis measured ∼66% co-localization between the lysosomal structures and the mutant bacteria (Fig. 6C).

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