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While the exact origin of the expression remains in some doubt, according to the reference guide "Brewer's Famous Quotations," the American labor leader Walter Reuther famously used it "as a test of whether someone was a Communist" during "the McCarythyite witch-hunts of the 1950s".
Yet the expression remains Greek, for the word thelgetai that Dionysius chooses is one that echoes the conclusion of Agathon's speech in the Symposium where Agathon praises a Love that everyone "should hymn fairly, sharing in the song he sings that enchants/charms/beguiles (thelgon) the thought (phronema) of all gods and human beings" (197c).
Today, the expression remains valid, but mostly for August.
The question of how smoking alters the expression remains unanswered and needs attention together with functional analyses of the identified genes in future studies.
With the transformation of cells into cancerous ones, the expression remains on similar level, but the correlation is lost.
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The lower right panel shows the effect of translation repression: in this case the mRNA expression remains unaffected, but the change in the mRNA-protein response curve leads to reduced protein expression.
Therefore, while the estimated expression levels of homoeologous genes in our database are, on average, slightly reduced due to their sequence similarity, the reported expression remains closely correlated with the true expression level.
What drives the elevated expression remains to be established; the 231-BR and 231-BR3 variants have constitutive activation of STAT3, which has been linked to elevated expression of various genes, including VEGF, cyclin D and survivin [ 27].
As the regulation of p50 gene expression in glioblastoma cells is still unclear, the mechanisms by which PHD2 maintains the p50 expression remains to be further studied.
hnRNPK was also found to exhibit post transcriptional regulation; once again the mRNA expression remains constant while protein expression increases.
While BRCA mutation carriers possess a 20-40% lifetime risk of developing ovarian cancer, knowledge about genetic modifying factors influencing the phenotypic expression remains obscure.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com