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Lovis, P., Gattesco, S. & Regazzi, R. Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs.
A fine balance exists in the expression of components of the plasminogen-plasmin system, whereby tissue homeostasis is maintained.
Additionally, the expression of components of the Toll-like receptor 4 (TLR4)/nuclear factor-κB (NF-κB) pathway, and the nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome were also assessed.
Although it has been demonstrated that several miRNAs directly regulate the expression of components of cell pathways relevant to radiosensitivity, and miRNA expression profiles change upon irradiation, understanding the causal role exerted by individual miRNAs in determining tumor radiation response is still at an early stage.
Genetic or acquired alterations in the expression of components of this system are strongly implicated in the pathogenesis of hypertension.
Conversely, these compounds also induce a decrease in the expression of components of the PI3K/pAkt, ERK1/2, and NF-kB/Akt signaling cascades which coordinately contribute to cancer cell survival [10].
Our data demonstrate that PRDM5 regulates the expression of components of both canonical and non canonical wnt pathways and negatively modulates wnt signaling in vivo.
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Alterations in the expression of desmosomal components could contribute to cancer progression similar to E-cadherin 11, E-cadherin 11r, the correlation between the expression levels of desmosomal components and the state of tumor development has not been fully established.
This demonstrates the importance of considering the expression of other components of the BER pathway when evaluating the impact of XRCC1 polymorphisms on cancer risk.
Transcriptome analysis revealed that CDK8 kinase activity is required for the expression of many components of the glycolytic cascade.
The unified method requires less supervision than the conventional SPM and enables classical inference about the expression of independent components.
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