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The parameter x sus strongly influences the expected work loss of people who take prophylaxis.
As a reference value, the expected work loss per person without prophylaxis is depicted as grey horizontal bar in Fig. 3c.
For strains with higher fitness, the expected work loss can be worse than without prophylaxis if 10% or more receive prophylaxis.
The expected work loss per person can approximately be calculated as follows: omitting antiviral treatment and prophylaxis, we expect about 75% of the population to become infected.
If all severe cases are treated, the expected work loss per person drops to 2.1 days if no NI resistance develops or if the NI resistant strain has a low fitness (with de novo development of a highly transmissible resistant strain, the expected work loss is only reduced to 2.4 days).
If only few people take prophylaxis (cf. Fig. 3c), the expected work loss varies between nearly 0 days (x sus = 0) and 1.2 days (x sus = 1) for low fitness values, and from 0.9 to 1.6 days for high fitness values.
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