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The overlap between the expected side effects of volasertib and the cardinal symptoms of AML, including myelosuppression, blood cytopenias, neutropenic fever and infection, make the assessment of AE with regard to relatedness challenging.
"Cosmetic surgery is the subject of a disproportionate number of complaints stemming from informed consent issues, largely due to the perceived failure of clinicians to communicate the likely outcomes of the procedure and the expected side effects," the forum said.
The expected side effects were mainly of low grade.
None of the pharmacies warned the patient of the expected side effects of the drugs.
At month 3, patients receiving CMF reported the expected side effects.
The sulphur sites corresponded to the expected side chains when compared within the density modified electron density map.
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SUSARs will be reported according to the relevant timelines; expected side effects will be reported in the annual safety report unless serious enough to warrant expedited reporting.
Three quarters or more of the GPs were influenced by two disease-linked factors, the seriousness of the cancer symptoms and expected side effects and tolerance of treatment.
Whilst any suspected, unexpected, serious adverse reaction (SUSAR) involving insulin therapy will be reported according to the timelines for SUSARs, expected side effects of insulin will be reported in the annual safety report unless serious enough to warrant expedited reporting.
The effective management of expected side effects associated with anticancer therapy is a key point in patients' global care.
None of the pharmacies provided counseling on expected side effects, nor queried about potential drug allergies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com