Sentence examples for the expansion and function of from inspiring English sources

The molecular mechanisms that promote the expansion and function of ABCs are largely unknown.

One of these groups also performed a series of experiments examining how ATRA affected the expansion and function of natural Tregs and concluded that ATRA augmented their suppressive activity and should therefore be considered for use in Treg-based therapy.

It is possible that some of their activities relate to disruption of mitotic memory functions required to sustain tumor cell growth or the expansion and function of immunocompetent cells.

In the present study, we show that testosterone and its active metabolite dihydrotestosterone exert no effects on the expansion and function of late endothelial progenitors isolated from the peripheral blood of healthy human adult males, whereas they positively modulate early 'monocytic' endothelial progenitor cells.

Finally, magnetic resonance imaging and positron emission tomography were used to monitor the survival, expansion and function of the grafted cells as well as the immune response in the host brain.

Based on these results, which indicate a role of RA in Treg stability, and considering the reported role of IL-2 on the development, expansion, and function of Tregs [ 30], we wondered whether RA and IL-2 affect either the expression of suppressive markers characteristic of Treg cells or the suppressive capacity of Treg cells.

The aim of this study was to determine if a single exercise bout would augment the ex vivo expansion and function of γ−δ T-cells using a clinical grade protocol designed to preferentially expand the Vdelta2 subtype.

Beginning in the thymus and continuing into the periphery, these interactions, refined by accessory molecules, direct the expansion, differentiation, and function of T-cell subsets.

Here we provide direct evidence that administration of recombinant IL-7 can potentiate the expansion, maintenance and function of adoptively transferred tumor-reactive CD4+ T cells (Fig. 4).

Knocking out the murine homologue of PTPN22 resulted in lower thresholds of T-cell activation and induced an increased expansion and function of the effector/memory T-cell pool, which was associated with elevated levels of serum antibodies [ 19].

3. Our findings suggest that LPS stimulated development, expansion and function of the immune system so that LPS-treated males were less susceptible to ANKENT development than LPS-untreated controls.