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The regression models produced three-fold greater HRs at the highest restricted exposure level than the expanded category model.
In the expanded category analysis of UG workers there are eight referents, while for the complete cohort there are 52 referents (Tables 4 and 6 ).
As there is no easy way to verify families that were placed into the expanded category due to high sequence coverage alone, our discussion below is limited to gene duplicates that were annotated in the D. buzzatii genome.
The untransformed regression model is a relatively good fit with the expanded category model up to the penultimate exposure category around 1280 µg/m years, but then it veers upward while the HR declines in the categorical model.
These continuous models are not biologically plausible and do not follow the expanded category model trends, and for most of the exposure range are either below or above the ORs of the expanded categories.
This HR of 5.01 is the highest HR in any of the expanded category models, indicating the strong effect of the a posteriori analyses, which excluded all workers with less than 5-years tenure: The authors' conclusion is based on workers with 15-year lags, exclusion of workers less than 5-years tenure, and cumulative exposures restricted to <1280 μg/m years for UG workers.
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SHARON H. KNEISS President, The Environmental Industry Associations Washington, May 1, 2013 To the Editor: Your editorial refers to the expanded categories of items that now "can finally go in clear recycling bags".
Among UG workers and over the full exposure range none of the E-R trends from the continuous models fit the expanded categories.
In the expanded categories the maximum HR of 8.68 (1.61–49.9) among surface workers is nearly twofold higher than the maximum HR of 5.01 (1.97–12.76) among UG workers at 640 1280 µg/m year in the 7th exposure category of the expanded categorical analysis (their Tables 4 and 5).
In the cohort study there are no trends in the 15-year lagged quartile analyses, although there was a positive slope for the 4th quartile, which in the expanded categories with <5-year tenure showed two-fold increased HRs, but with few workers.
Including Jews in the expanding category of "whites" provided Jewish families with access to a wealth of opportunities denied people of color.
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