The examination will include a 3D T1-weighted sequence an axial T2 sequence an axial T2* sequence and an axial FLAIR sequence.
The Otolaryngologist, upon assessing a patient with chronic cough, will take a careful history and the examination will include endoscopy of the nasal cavity, larynx and pharynx.
The examination will include assessments of the wearing of dentures; history of orthodontic treatment; the health of oral mucosa; tooth loss, presence of decay, and dental treatments; plaque, calculus, gingivitis; periodontal tissue destruction; decay experience of coronal and root surfaces; and the presence of enamel defects.
The clinical examination will include tests for impingement [ 10], pain or weakness on isometric tests of abduction and external rotation [ 11, 12], tests for apprehension and relocation [ 13], scapular dyskinesis [ 14], and arthritis of the acromioclavicular joint [ 15].
The major safety end points are set in the J-BRAND Registry study as below, and the baseline physical examination will include an assessment of these end points.
The new follow-up examination will include the collection of new biological samples suitable for all planned biomarker and omics analyses (research areas 1 and 4, below).
The follow-up examination will include anthropometric measurements, evaluation of blood pressure, vision, hearing, incontinence, anamnesis, performance testing, ADL, GDS-15, MMSE, Tinetti Test, GFI, LOC, grip strength, spirometry, ECG, bio-electrical impedance, exhaled NO, echocardiography and new blood tests.
Physical examination will include the ULNDT1.
Physical examination will include the assessment of cardiovascular risk factors and prevalent cardiovascular disease.
This consultation, besides the standard interview and clinical examination, will include collection of information related to BPSD (NPI and Apathy Inventory) and any factors which may influence behaviour, in particular environment data, caregiver's burden and concomitant diseases.
Physical examination will include bilateral measurement of the active range of motion of the shoulder, elbow flexion and extension and forearm pronosupination with a goniometer.
