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For the comparison between the groups, no statistically significant difference was found between the NMES + Ex and the Ex groups in NRS (P = 0.52), TUG test (P = 0.12), and aspects of WOMAC: pain (P = 0.26), function (P = 0.23), and stiffness (P = 0.63).
The Ex groups received a 15-min training regimen on a motorized treadmill 5 times a week.
However, energy intake was ~37% lower in the CR than in the EX groups.
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There was a significant improvement in all WOMAC subscales in the NMES + Ex group (pain; P < 0.0001; physical function, P < 0.0001; stiffness, P < 0.0001) and in the Ex group (pain, P < 0.0001; physical function, P < 0.0001; stiffness, P = 0.0009).
There was a trend for leptin levels to decrease in the EX group (P =.06).
Of the 13 dropouts, 6 (12%) patients were in the NMES + Ex group and 7 (14%) in the Ex group.
Patients in the Ex group performed the same exercise program as those in the NMES group but without NMES.
The anaerobic threshold was significantly increased in both the MEx group and the Ex group (Table 3).
Subjects in the Ex group completed the exercise protocol and then proceeded with the same schedule as the NEx group.
The NOEX group exhibited a significant reduction in VO2peak, while the EX group maintained VO2peak during weight regain (Table 1).
The urinary concentration of Aggrecan was significantly elevated in the Ex group at T1 compared to T2.
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