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Simple public health measures, like hand washing, will decrease the infectious inoculum, help prevent disease outbreaks, as well as promote the evolution of less virulent pathogens.
For acute infectious diseases, interventions that selectively reduce the transmission from the sickest individuals will favor the evolution of less virulent pathogens.
In general, does enhanced robustness lead to improved system performance but also the evolution of less costly, lower performance components?
Relevant to this, we showed in earlier work that CpG dinucleotide retention in coding sequences correlates with codon essentiality [21], [22], whereas both gene methylation and intron length accelerate the evolution of less well repaired downstream intragenic sequences [23].
However, there may be opportunities for exploring the evolution of less industrialised livestock farming models that are amenable to mixing with energy crops.
In conclusion, the early dynamics of the development of resistance to an aminoglycoside antibiotic is dependent on the levels of stress (concentration) imposed by the antibiotic, with the evolution of less costly variants only a matter of time.
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I remember in army days reading of a youth who, being examined for the lowest grade and being asked a question about squadron drill, answered that he never had considered the evolutions of less than ten thousand men.
The outcome of a different experimental design in which transmission would be vertical, and hence making high virulence detrimental, or in which virus and host are engaged in a coevolutionary arms-race may produce different results; perhaps with the evolution of a less severe virus and different alterations in plant gene expression.
Thus, pathogenic lifestyle affected the evolution of no less than 1828 gene families, about 30% of the E. coli pangenome.
Furthermore, the study of more advanced (in terms of road safety and in general) countries may be applied to predict the future evolution of less developed or successful (in terms of traffic safety) countries.
The vital place of literature and the figure of the writer in Russian society and history have been extensively studied, but their role in the evolution of psychiatry is less well known.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com