Thus, the stromal (fibrotic) compartment in the MG may provide the essential stimuli for the transition of N-cad from its adhesive to an oncogenic function.
When the economy was imploding only three Republican senators voted for the absolutely essential stimulus bill; none agreed to back health care reform or even vote to end a filibuster.
In fenretinide-treated cells, ROS signaling may represent an essential stimulus at the early stage of programmed cell death.
An Engels quotation loomed over a set of wooden display cases: "First labor, and then speech these were the two most essential stimuli under the influence of which the brain of the ape gradually changed into that of man, which, for all its similarity, is far larger and more perfect".
Monti did not get German approval to adopt the essential fiscal stimulus programs.
More recently, Yamamoto et al.[ 42] demonstrated the secretion of placental lactogen (elPL) by elephant trophoblast tissue and speculated that this chorionic hormone may be the essential luteotrophic stimulus for the enlargement of the fetal gonads and their synthesis of progestagens to assist the accessory corpora lutea in the maternal ovaries to maintain the pregnancy state.
This mechanism, in which extracellular Wnt ligands provide an essential stimulus for cell proliferation, is distinct from that commonly found in human colon cancer and several other forms of cancer, in which constitutive activation of Wnt signaling is a consequence of mutations in downstream cytoplasmic elements such as APC, CTNN1 (encoding β-catenin) or AXIN2 [3].
This is an economical arrangement since the animal tends to respond only to essential stimuli, the brain having little to do but relay signals to the motor system.
Instead, instability exercises accounted for increased activity in the stabilizing muscles and, thus, provide essential stimuli for their neuromuscular adaptation [ 6].
As outlined at the outset, it is commonly thought that the timing of individual spikes is rather random, and that the essential information about stimulus attributes is conveyed by an average across intervals in the 20 200 ms range.
So far, we have considered the essential neural mechanisms of stimulus processing in the ascending pathway.
