Sentence examples for the essential regulators from inspiring English sources

One of the essential regulators of this pathway that is significantly altered in GBMs (30 40%) is the PTEN tumour suppressor gene1,3, which encodes a phosphatase responsible for the removal of phosphate from the 3′ position of the phospholipid second messenger phosphatidylinositol-3,4,5-trisphosphate, thus opposing mitogenic signalling mediated by class 1 phosphatidylinositol 3-OH kinases4.

Akt serine/threonine kinases are one of the essential regulators of cell survival function in response to growth factor stimulations (12, 13).

Taken together, our observations suggest that this Rheb GTPase homolog and the TOR signaling pathway functions as one of the essential regulators during fruiting body formation.

According to our hypothesis that MaSCs is the source of BCSCs which proliferate and differentiate into breast cancer cells, miRNAs with consecutive changes from MaSCs to BCSCs to MCF-7 cells would more likely be the essential regulators of self-renewal of BCSCs.

Hubin, E. A. et al. Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA.

It has been proposed that Ikaros, and not Aiolos is the essential regulator of the VpreB/λ5 locus [45], [62].

Taken together, IL-10 seems to be the essential regulator, which transmits cardioprotection following ODN-priming.

The balance between the activities of MMPs and MMP inhibitors is the essential regulator of ECM degradation and, consequently, of cellular phenotypes related to motile and invasive capacities.

The authors conclude that Wnt signalling provided by the adult pancreatic and neural niche cells represents the essential regulator of insulin-expression during this process.

Riboflavin has been reported to induce resistance to fungal and other pathogens [ 73], potentially by recruiting NPR1, the essential regulator of systemic acquired resistance, independently from the defense-signaling hormone salicylic acid, which is strongly associated with NPR1 [ 74].

Particularly for those progenitor cells reside in hypoxic niches, glycolytic and anaerobic respiration is a preferred energetic pathway and CtBP could be the essential regulator to support their self-renewal and pH homeostasis.