A genome represents the entire complement of genetic material in a chromosome set, with a well-defined, fully sequenceable endpoint.
The genetic code in the DNA of virtually every somatic cell can produce the entire complement of encoded proteins.
The prime goal of the 100,000 Genomes Project is to sequence the entire complement of genes possessed by around 70,000 individuals in the UK.
Two Gateway-based libraries of overexpression plasmids containing the entire complement of yeast open reading frames (ORFs) have recently been completed.
She again descends to the pond and repeats the performance at a different site until the entire complement of eggs is deposited.
DarwinOncoTreat homes in on the entire complement of master regulator proteins responsible for launching and maintaining a specific tumor to predict the drugs that, by interfering with these proteins, will most likely benefit the patient.
To achieve this capability, the team's approach leverages the entire complement of human transcription factors (TFs), the proteins that directly regulate the expression of genes required for the differentiation and function of a given cell type.
This is to identify and characterise the human "proteome", the entire complement of proteins encoded by those genes.The task is monumental because the process of translating genes into proteins is not as simple as it once seemed.
The elucidation of the entire complement of genes encoding protein tyrosine phosphatases (PTPs) in human genome, the human 'PTPome', has made it possible to experimentally address the entire family in an unbiased manner.
We have developed a high-density peptide chip technology that allows for probing of the affinity of most SH2 domains for a large fraction of the entire complement of tyrosine phosphopeptides in the human proteome.
"We are going to sequence in depth the entire complement of genes in a healthy labrador retriever to ensure we have a perfect, accurate picture of the basic genetic structure of one of these dogs," says Dylan Clements, the Roslin researcher who is leading the project.
