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Another surprise was that the engineered mice had less breast tissue, meaning that EDAR could be the reason that East Asian women have generally smaller breasts.
When new mouse "models" of human disease are created by genetic engineers, Dr Mogil and his colleagues are often asked to test the engineered mice for their responses to pain.
As expected, the engineered mice didn't go through puberty.
The engineered mice lived an average of 38 weeks, compared to 12 weeks for dystrophic mice.
They sacrificed some of the engineered mice and isolated a slice of the light-sensitive somatosensory cortex, which remained viable for several hours.
For example, when placed on a warm surface, the engineered mice overreact, immediately lifting their paws rather than first exploring the surface.
Similar(39)
To the surprise of the researchers, the genetically engineered mice also had more sweat glands.
The scientists found the genetically engineered mice could run twice as far as normal mice, and they stayed lean even when they were fed on a high-fat diet.
Compared with normal mice infected with the foot-and-mouth disease virus, the genetically engineered mice showed little sign of the disease in their bodies.
The researchers, at Massachusetts General Hospital in Boston, report in the journal Nature that the genetically engineered mice produced omega-3 fatty acids, a heart-friendly substance normally found in salmon and other oily fish.
Even on these low doses of nicotine, the genetically engineered mice still exhibited the classic symptoms of addiction.
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