By the electrochemical etching we observed ivariably 〈1120〉 pit orientation (and, perhaps, in connection with this the appearance of non-symmetrical etch pits on the emergence points of screw dislocations with the Burgers vector 13 〈1123〉).
In this way the emergence points of screw and edge dislocations have been distinguished, the former being developed by deep pyramidal etch pits whereas the latter created flat-bottomed pits.
Superficially, top and right views look like reflections of one another in a vertical mirror, suggesting they may be related by a rotation of ∼180°, but the similar emergence points of the stalk and the positions of the tags, most notably B2 and B5, rule this out.
Treatment for chronic hepatitis B with lamivudine is often hampered by the emergence of point mutations in the YMDD motif of the HBV DNA polymerase gene that confer drug resistance.
Imatinib, which targets the ATP-binding site, is effective in the early stage of the treatment of Ph-positive patients, but advanced-stage patients may relapse as a result of the emergence of point mutations within the Bcr Abl.
Resistance frequently results from the emergence of point mutations within the kinase domain of the BCR-ABL protein that reduce the binding affinity of imatinib, although it is occasionally associated with amplification of the BCR-ABL gene (Gorre et al, 2001).
We then analyzed the patterns in which these disease genes emerged within the Metazoa using phylostratification, a process by which genes are placed into major taxonomic groups ("phylostrata") according to their inferred evolutionary emergence point [ 42].
The absence of or the delay in the emergence of pointing behavior in autistic spectrum conditions led to the hypothesis of a deficit in a 'Shared Attention Mechanism' (SAM) [15], [16].
The emergence time points of the major and minor categories of molecular functions in the timeline of FFs revealed remarkable patterns of origin in the five evolutionary phases.
