Finally, we tested whether the effects of binary combinations of agents with strictly different mechanisms of actions could be approximated by IA.
Therefore, the effects of binary combinations of organic acids on the cell growth and lipid accumulation of T. fermentans were tested at their respective IC25 concentrations listed in Table 2. Acetic and 4-hydroxybenzoic acids, the typical aliphatic and aromatic acids in lignocellulosic hydrolysate, respectively, were chosen for binary combinations with other organic acids.
Sequence-dependent cytotoxic effects of binary combinations of ZD1839 (0.2 200 μ M) with ionising radiation were then evaluated using eight doses of ionising radiation, ranging from 0.5 to 10 Gy for CAL27 and CAL33, and from 2 to 15 Gy for CAL60, CAL166, Hep-2 and Detroit562 (the radiation doses were selected from the above experiments to encompass more precisely the zone of sensitivity).
Secondly, $f$ changes under the effect of binary collisions only.
The effect of binary toxin in animal studies of CDI has been difficult to assess.
Heat map representing the effect of the binary combinations for rosette and leaf area.
10.7554/eLife.02252.072 Figure 3. Heat map representing the effect of the binary combinations for rosette and leaf area ( A ) in reciprocal heterozygous crosses and ( B ) homozygous lines.
The equation of the model easily clarifies the effects for binary combinations of the independent variables.
The effects of binary and ternary combinations of ground granulated blast furnace slag (GGBFS), fly ash (FA) and silica fume (SF) on compressive strength, flexural strength, water sorptivity, permeable voids and drying shrinkage of steam cured alkali-activated cement (AAC) mortars were investigated within the scope of this study.
In subchallenge2, a weighted Euclidean distance method is introduced to predict the sensitivity of binary combinations of drug compounds and whether they have a synergic effect on reducing the viability of the DLBCL cell line.
