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This observation was noted to be of interest as the gdv1 gene is the earliest marker of parasite differentiation from asexual replicating blood stages into sexual stage gametocytes which are transmitted to mosquitoes15,16.
Mesp1 directly and/or indirectly regulated the expression of the majority of key cardiovascular transcription factors including Hand2, Myocardin, Nkx2-5, Gata4, Mef2c, Foxc1, and Foxc2, thus acting as a master regulator and the earliest marker of cardiovascular development in vertebrates and cardiovascular differentiation in mammalian pluripotent stem cells.
Zebrafish foxi1 is the earliest marker identified as being expressed in the otic placode.
In this study, we also demonstrated that foxi3a is the earliest marker expressed in epidermal IC progenitors.
Whi5 enters the nucleus shortly before division and its exit from the nucleus is the earliest marker available for the Start transition[21], [22].
In this respect, the identification of Sox2 transcripts as the earliest marker of inner cells of the embryo should be noted [19].
Similar(29)
The first gradient occurred in the cortical ventricular zone and established ephrin-A5 as one of the earliest markers distinguishing cells residing in the anterior versus posterior cortical neuroepithelium.
In other words, the detected increments of the cell stiffness resulted from interaction with silica-based NPs, which may serve as one of the earliest markers of their cytotoxic effect.
Soul food represents one of the earliest markers of African American resistance, and Tillman Jr. illustrated that resolve and determination throughout his film.
And in both cases the treatment can be traumatizing for many (women losing their breasts, men becoming impotent or incontinent), amplifying fear in the general public of even the earliest markers and least lethal forms of these cancers.
CD34, CD150, and c-Mpl could be good candidates for the earliest markers during HSC development.
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CEO of Professional Science Editing for Scientists @ prosciediting.com