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With headquarters in London, the company initially has a portfolio of 10 licensed drugs, including some of the earliest, like AZT and lamivudine, and later ones, like maraviroc, with combined sales of about $2.7 billion in 2008.
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The earliest beetle-like species during the Permian had pointed, leather like forewings with cells and pits.
The earliest tree-like organisms were tree ferns, horsetails and lycophytes, which grew in forests in the Carboniferous period.
It is found that the large droplet size together with fairly high-speed in the early jet-like spray leads to highly efficient surface cooling.
This indicated that Ras is active on macropinosomes at the early endosome-like stage, consistent with earlier studies (Porat-Shliom et al., 2008).
Furthermore, MF-disruption-induced malformation of the cell plate suggests that MFs regulate the early disc-like morphology of the cell plate.
Retrospectively, accidental intravenous injection of MALP-2 could not be rigorously excluded as aspiration was not performed in this patient to explain the early shock-like symptoms.
Chance mutations that directly reverse or otherwise suppress the earlier mutator-like mutations in Geraniaceae may be favored and fixed by natural selection.
The earliest mammals, like their reptilian ancestors, were active predators.
The earliest scriptures like the Vedas, Upanishads and Brahmanas connect the epithet to Indra, the king of the gods and the Supreme god of the era.
The earliest rhino relatives like Hyrachyus are barely distinguishable from contemporary tapiroids (Fig. 4) in the early middle Eocene.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com