Your English writing platform
Discover LudwigExact(2)
2) Tubular variants of round structures were among the earliest coat structures ever examined by electron microscopy - the polyheads of T4 and related bacteriophages, studied in detail by Kellenberger and Klug in the '60s.
In the first, each vertex would have the same orientation relative to the tube (left-hand panel)…" 2) Tubular variants of round structures were among the earliest coat structures ever examined by electron microscopy - the polyheads of T4 and related bacteriophages, studied in detail by Kellenberger and Klug in the '60s.
Similar(58)
Only the matte areas on the clock face are from the earlier coat of paint.
Another feature of the early coat is the differential spatial behavior of its constituents.
Thus, many questions remain open about its recruitment to the early coat and/or the plasma membrane and how it interacts with other early coat proteins.
The first middle coat proteins to join the early coat patch are likely to regulate the transition between the end of the early coat-based initiation phase and the next step in endocytosis.
The early coat protein Pal1 is another member of an Ede1-containing complex (Gavin et al. 2002; Carroll et al. 2012).
Initially, characterization of the temporal and spatial dynamics of endocytic proteins had not included the early coat proteins and was focused on the immobile coat proteins that became mobile when F-actin appeared (Kaksonen et al. 2003).
Whatever the precise cause of temporal variability, it is clear that some trigger causes a transition within the early coat proteins and/or the underlying membrane that allows the next wave of proteins to join the endocytic site.
Another question is how yeast clathrin is recruited to these sites, since none of the early coat proteins are known to bind clathrin, with the possible exception of YAP180 (whose arrival time is debated in the literature; see below).
Third, an interaction between Sla2 and clathrin light chain in turn affects the timing of Sla1 recruitment (Newpher and Lemmon 2006; Boettner et al. 2011), suggesting that the early coat together with Sla2 influences later stages of endocytosis.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com