Rotator cuff is a vital structure of glenohumeral joint, the dysfunction of which leads to debilitating pain and restricted movement.
Primary sensorimotor cortex is the key structure of sensorimotor circuits, the dysfunction of which has been recognized as a crucial reason for motor difficulties in PD [ 32].
The close functional and molecular integration of the immune and metabolic systems is emerging as a crucial homeostatic mechanism, the dysfunction of which underlies many chronic metabolic diseases, including type 2 diabetes and atherosclerosis.
The decreased connectivity pattern revealed the dysfunction of MrD, which could explain the role of MrD in migraine chronicization.
Finally, acetyl-tubulin evaluation, and SV transport assays on SPG11-dNeurons pointed towards the dysfunction of SPG11, which leads profound deregulation of the axonal stability and transport.
We have identified several new members of the MID1/α4 complex, dysfunction of which underlies the pathogenesis of OS.
Our findings point to a specific maternal expression of CADPS2 in the blood, but also in the amygdala, that plays a critical role in social behavior (as part of the "social brain") and dysfunction of which has been implicated as a contributing factor in ASD (Schultz, 2005).
Inflammation out of control caused by sepsis can eventually lead to multiple organ dysfunction, of which the kidney is one of the most common injured organs.
Some of the secreted Aβ oligomers enter the cell through selective uptake and subsequently cause the dysfunction of subcellular organelles, which is associated with the memory and cognitive decline typically observed in AD patients[30].
STZ is a substance specifically toxic to pancreatic β cells, and the damage STZ causes to β cells leads directly to the dysfunction of β cells which can not be easily reversed.
Osteoarthritis involves mainly the dysfunction of articular chondrocytes, which leads to cartilage degradation through chondrocyte maturation and MMPs production [ 3, 4].
