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The duplication results in the partial duplication of two genes: PRLR and SPEF2.
The duplication results in the start codon of the second copy of patA being located 365 bp downstream of one of the five copies of a glutamate-specific tRNA gene found in the R6 genome.
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In our study, an effect of altitude could not be confirmed as the duplication resulted conserved in Quechua-Cusco and Quechua-Lamas, similarly to Amazonians.
The duplication resulted in an increased expression of lamin B1 mRNA and protein in patient brain tissue [ Padiath et al., 2006].
The duplication resulted in the partial duplication of two genes; the prolactin receptor and the gene encoding sperm flagellar protein 2. Furthermore, a DNA test was developed to distinguish between homozygous and heterozygous late feathering males.
We conclude that the EMS-induced mutations are homozygous along chromosome I homologs and differ from the wild-type alleles on the duplication, resulting in an allelic ratio in the range of 70 80%.
Rapid divergence in gene expression profiles of duplicates following the duplication event results in expression profiles as diverse as those of singletons.
One of the duplications resulted in the genes for the two Obp1 subunits, Obp1a and Obp1b.
We did not find triple alleles in any of the samples strongly suggesting that the duplications resulted from intrachromosomal rearrangements.
Dot plot analysis indicated that the duplications resulting in the 9 sub-loci were limited to the I2 sequences but not their flanking regions, since sequences flanking these I2 homologues are unrelated (Additional file 2: Figures S1 and S2).
Regardless of the exact scenario for the duplication event, the results point to conservation of DNA sequence OPs that are distant (10 100 kb) from the genes' edges.
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