Sentence examples similar to the drivers network from inspiring English sources

GATA3 was included in the driver network for the "differentiated subtype" with relatively good survival outcome, although GATA3 mRNA was not significantly up-regulated in this subtype.

Experimental validation of the driver-network genes has shown the functional importance of the results.

If a gene passed either one of these tests, it was included in the driver-network.

These two genes were present in the driver-networks obtained from our analysis.

To test whether the driver-networks are significantly reproducible, we examined the overlap between subtype-specific driver-networks in the two data sets.

At the same time, the driver-networks from the same clinical subtype were significantly reproducible across independent data sets.

This random sampling was repeated 1000 times and only those genes that appeared in at least 50% of the driver-network samples were included in the final driver-network.

For example, ESR1 and many of its interacting partners in the driver-network (e.g., TFF1, XBP1, IGF1R, AR, CELSR1, and RARA) are significantly over-expressed without amplification.

However, these other genes were not hubs in the Andre et al (2009) data set, possibly because the driver-network itself was much smaller.

In the Supplementary Information (SI) we have also included the driver-networks using seed genes from the Chin et al (2006) data set.

In all of the driver-networks, we found that most of the genes were either directly or indirectly connected to each other, creating a main component.