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A neuroethicist can look at the downstream implications of these new possibilities.
Nobody can know all of the downstream implications of driverless cars.
What are the downstream implications of your actions?
However, the downstream implications of such short-term fluctuations in serum concentration for glucocorticoid action on target tissue have not been explored.
Our hope is that once a treatment for CMT1A is approved more drug companies will be interested in CMT, investment in research will increase and therefore we have to be prepared for that and the downstream implications on resources, research materials, researchers and ultimately patients themselves.
Previous analyses of the costs of screening have often focused only on diabetes, have not compared different screening strategies, or have examined screening in only limited ways, e.g., have not included the downstream implications of detecting diabetes as well as pre-diabetes or have ignored the costs of false-negative and false-positive screening results (6– 12).
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Due to the broad downstream implications of TLR4-mediated signalling, TLR4 ligands show great potential for immunotherapeutic manipulations.
The most immediate downstream implications of impaired activation of Stat1, a transcriptional regulator, should be reduced induction of target gene transcription by agents that signal through Stat1.
Xion et al. had reported dysregulated mir-203 and mir-350 that have downstream implications on the Nlk, Sema5a and Acer2 genes, vital in the regulatory network86.
It incorporates downstream implications at the fundamental molecular level.
Since reconstitution of the naïve T-cell compartment contributes to reconstitution of overall CD4+ T-cell counts, a continued deficit in naïve CD4+ T-cell numbers would have downstream implications for the effector/memory compartment.
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