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The downstream consequence is a distinctive shift toward specific hybrid and complex N-glycans on N-glycoproteins produced from XBP1s-activated cells, which we characterize by mass spectrometry.
In a long term, it benefits to develop medication that enhances DNA damage but sever the signaling pathway arising from DDR events to the downstream consequence, DDSP program development, thereby depriving cancer of acquired resistance and reducing disease incidence, progression and mortality.
Intermittent hypoxia also activates pro-inflammatory transcription factors such as nuclear factor kappa B that promote activation of various inflammatory cells with the downstream consequence of expression of pro-inflammatory mediators that may lead to endothelial dysfunction [40].
Importantly the downstream consequence of these actions, was that Pred could modulate thrombus formation in vitro under conditions of flow.
In this scenario, ArcLight responds primarily to the downstream consequence of a membrane voltage change (decreased pH) and not directly to the voltage change itself.
The downstream consequence of TLR-4 signaling is IL-12 cytokine secretion (Palsson-McDermott and O'Neill 2004), which is a strong promoter of Th1 development.
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The downstream consequences of that legislation are now generally accepted.
"Think about all the downstream consequences of that,'' he said.
It means regularly monitoring both the output of algorithms and the downstream consequences.
We show that wealth visibility facilitates the downstream consequences of initial inequality in initially more unequal situations, wealth visibility leads to greater inequality than when wealth is invisible.
The power of that influence may not be clear to managers, just as the downstream consequences of staying connected to work on vacation may not be intended.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com