Sentence examples for the dissolution parameters from inspiring English sources

On the other hand, the matrix variables were non-significant to the dissolution parameters.

Circular dichroism, thermoporometry, FTIR, impedance and scanning electron microscopy techniques have been employed to investigate the effect of PCL on hydration dynamics of the collagen molecule, which in turn changes the dissolution parameters of the drug from the systems.

The dissolution parameters of the passive film were calculated from both EIS and polarization measurements and the activation energy of the dissolution process in the different solutions was calculated.

To get an estimate of the performance of the drug delivery system from the preliminary investigations [ 7], the following dissolution parameters were considered as responses of the variables.

The amounts of PEG-4000, PVP K30, HPMC K100 and HPMC E50LV were used as independent variables following a statistical experimental design, and three dissolution parameters (time at which the 90% of the drug was dissolved, t90%, percentage of nimodipine released in 2 and 8 h, Y2h, and Y8h, respectively) were chosen as response variables.

Multivariate regression was built between the NIR scores as the predictor variables and the dissolution profile parameters as the response.

Finally, artificial neural networks, used to correlate the examined formulation and process variables of hot melt mixing with dissolution parameters, showed good prediction ability.

Measured hydraulic properties, residual saturations, and dissolution parameters were employed in these simulations.

Table 2 Dissolution parameters for drug release from nanoparicles for Korsmeyer Peppas kinetics Formulation Correlation co-efficient (R2) Release exponent (n) Release constant (k) ETN 0.974 0.571 7.194 QDN 0.911 0.714 4.187.

Responses studied included similarity of dissolution profiles, time for 60% of the drug to dissolve (T60%), percent of VP released after 7h (PD7 h) and the dissolution efficiency parameter at 12 h (DE12 h).

Therefore, to characterize the drug release rates in different experimental conditions, another dissolution parameter used for comparing the formulations was mean dissolution time (MDT).