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I agree, there's nothing wrong ramping up the difficulty to provide players with a challenge, but for a game to be challenging rather than unfair, the mechanics the player relies upon need to be rock-solid, and in Spec Ops: The Line, they just aren't.
The reasons why this approach is less effective in inducing clinical benefits include the difficulty to provide enough stimulatory co-signals to exceed heavily overweighted inhibitory conditions in the tumor microenvironment.
The main reason relates to the difficulty to provide adequate human resources that would work for such a long period on the epidemiology of tuberculosis; however, even if a careful case-by-case analysis of the patient file data could not be assessed within the frame of the study, we fully assume that our results are a mirror of the epidemic situation of tuberculosis in French Guiana.
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They concluded that among others that lack of formal training and a lack of recognition of PSA as a specialised EM skill contributed to the difficulties to provide paediatric PSA in the ED [13].
Again, the CL soils are difficulty to provide sufficient bearing capacity to support the weight of the surface structure alone.
It is obvious that Canada would have had difficulty to provide me [with] a similar environment.
However, the main difficulty to providing care for families lies at present in the dearth of any family or child-focussed psychosocial services within oncology.
Numerical models, even state-of-the-art, have difficulties to provide independent predictions, because input data are scarce and sometimes tentative.
Difficulties to provide aviation systems with effective ISHM system.
The difficulty was to provide adequate room for all these sacred images, and so it consists of a triple arched gallery topped by a pyramid shaped roof.
In [1], we proposed a possible way to overcome the difficulty and to provide nonzero matrix element values for transitions of interest by tilting the magnetic field with respect to the structure layers.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com