The difficulties remain enormous.
The difficulties remain in the identification of evidential documents and valid relations between entities on the one hand and the adherence to time limits and data privacy-protection on the other.
This chapter discusses that the development of numerous biodegradable polymers for drug delivery applications has been significant but the difficulties remain for researchers who hope to produce efficacious drug release profiles, all while avoiding pharmacological or toxicological effects from the base polymer.
Although the points involved are larger than that involved in two-point BC, the difficulties remain similar.
As mentioned above, although other two hypothesis can partially explain the incongruence of the gene trees and positive selections of lys2, the difficulties remain in all of the hypotheses.
However, affordability difficulty remained the common barrier for the rural elderly to access quality health care, in spite of the special considerations given to the rural elderly, such as premium remission and free check-ups.
As the five-year extension expired the financial difficulties remained, and under pressure from shareholders the London Necropolis & National Mausoleum Amendment Act 1869 was passed.
Considering the realistic difficulties remained in calculating the Bhattacharyya parameters and likelihood ratios, unfortunately, the classical polar coding scheme only limited to a 2 × 2 matrix ( left[begin{array}{l}1kern1em 0 1kern1em 1end{array}right], ) which may lose its effect when flexibly applying other l × l matrix instead.
In keeping with our results, previous research on health technology assessments has found that those responsible for considering modelling evidence often display a good understanding of the principles underpinning the models but difficulties remained in communicating the level of uncertainty and the importance of assumptions underlying modelling evidence.
Hamilton's one disconcerting moment came at the treacherous Abbey Corner, where nine drivers had difficulty remaining on the track in the course of the afternoon.
"The same areas of difficulty remain," Hague said.
