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Recognizing potential false positives from adopting the Bloom filter, consideration of reducing it per the Bloom filter's design parameters is discussed, while the difficulty of utilizing the false positives due to hashing based indexing of the Bloom filter for malicious attack is noted.
This consideration highlights the difficulty of utilizing the CSC theory to design new strategies against cancer, since it can be inferred that it will be necessary to effectively target both CSCs and non-CSCs or multiple marker populations in order to achieve true therapeutic benefits.
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Other sources of variability could be related to the cut off values used for PCR detection or to the fact that only half of the patients studied had reliable information in regards to the gene expression, thus underscoring the difficulty of realistically utilizing this assay for clinical purposes.
All of these factors increase the complexity and difficulty of utilizing a single type of dressing.
Despite papers citing their diagnostic utility, limited clinical use of these agents may have resulted from logistical difficulties of utilizing these in everyday workflow, safety concerns, and lack of commercial success, resulting in their non-availability[ 1 3].
One aspect that was not considered in this study was the difficulty of the histological glass slides utilized in the circulations.
The case study highlights the difficulty of governments to make use of economies of scale and produce low-cost medicines, attract technology transfer, and utilize the flexibilities of the WTO Agreement on Trade-Related AspecTRIPS InTRIPScTRIPSProperTRIPSghTRIPSRIPS).
To relieve the difficulty of key distribution, a structured spiral phase key (SSPK) is utilized instead of the random phase key (RPK).
To address the difficulty of seeking a linear discriminant hyperplane in the tensor space, TLMMC utilizes a set of local multilinear hyperplanes to construct a global nonlinear one.
Due to the difficulty of gene expression profiling from FFPET using microarrays, several groups have utilized RT-PCR to quantify the expression of targeted sets of genes [29], [30], [65].
Under certain emergency circumstances (e.g., severe head trauma or suspected cervical spine injury), it may be impossible to fully utilize these the physical examination and the various classification systems to predict the difficulty of tracheal intubation.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com