This difficulty notwithstanding, several hypotheses have been put forward that explain the origin of different eukaryotic organelles.
All these difficulties notwithstanding, it seems that we have identified a parameter that may be associated with cetuximab clinical benefit.
53 These difficulties notwithstanding, it would be immensely valuable to identify bone change-related genes because many may fall in pathways that are more amenable to therapeutic modification than pathways specific for bone acquisition.
The difficulty in seeing it notwithstanding, Mercury was known at least by Sumerian times, some 5,000 years ago.
Notwithstanding the difficulty of defining its 'concentration' in serum73, as most of it is bound to macromolecules, it is known that in type 1 diabetes the serum load of endotoxin (LPS) is raised relative to that of controls86, and that this is associated with disease progression87.
Notwithstanding the difficulty of an organization to classify itself as an "affiliate entity" of LSC, Gozdor argued that there was no real prevention of speech when there were ample alternative means of relaying the message.
Notwithstanding the difficulty of assessing the generality of the results, due to the fragmentary knowledge about the complete set of cellular LMs, distinct evolutionary patterns were identified.
Notwithstanding the difficulty of obtaining primary effectors in large quantities from tumor infiltrating lymphocytes, the present study shows that anti-4-1BB has a much more substantial effect on enhancing granzyme B expression in reactivated memory T cells as compared to its minimal effect on primary effectors (Fig. 4F).
Notwithstanding the difficulty of changing eating habits, this study adds further support to the need for targeting in elaborating health and nutrition campaigns.
Notwithstanding the difficulty in proving that these candidate regions in fact reflect the action of positive selection (Hernandez et al. 2011), they display an outlier pattern of diversity that is consistent with positive selection and are enriched in true positives.
Notwithstanding the difficulty in drawing any definite conclusions from incomplete evidence and occasionally even contradictory results, recent findings indicate that an early onset of chronic pelvic pain at the time of menarche represents a risk factor for severe endometriosis during adolescence.
