Sentence examples for the difficulty is exacerbated from inspiring English sources

The difficulty is exacerbated by the well-known "probe effect" whereby the act of monitoring performance affects the performance itself.

The difficulty is exacerbated by the fact that one of the goals of evolutionary taxonomy is to identify taxa that were ancestors of other taxa.

The difficulty is exacerbated when severe teeth malocclusion and crowding problems occur, which is a common occurrence in clinical cases.

Because of differences in some properties and in the mechanism of origin between murine and human Th17 cells, it is difficult to identify the role played by this novel member of the CD4+ T cell effector family in the pathogenesis of human disorders; furthermore, this difficulty is exacerbated by the paucity of information currently available.

In such cases, it is difficult to precisely identify differentially expressed genes using traditional statistical methods, and this difficulty is exacerbated when the sample size is small.

It would appear that this difficulty is exacerbated for individuals with CHD and has not been fully acknowledged, explored or discussed with patients in practice.

This difficulty is exacerbated when the disease occurs for the first time because cholera awareness and preparedness will be weak, as can be seen in the early management of cases during this outbreak.

This difficulty is exacerbated in the case of congested networks by the so-called anticipatory route guidance problem (ARG problem, e.g. [16, 24]).

This difficulty is exacerbated at the Notch opa region when reads are aligned to the reference iso-1 assembly (isogenic strain with genotype y; cn bw sp) because it contains a minor synonymous polymorphism (5 ′ -CAG → 5 ′ -CAA; see Figure 3) (Brizuela et al. 1994; Adams 2000).

That difficulty is exacerbated by cuts in legal aid for welfare rights advice and cuts in local authority grants.

This difficulty is exacerbated for DAT and other pre-synaptic transmembrane proteins that still lack comprehensively described neuronal trafficking mechanisms.