The phrase "the difficulty in which" is grammatically correct and can be used in written English.
It is typically used to introduce a subordinate clause that explains or elaborates on a specific difficulty mentioned in the sentence. Example: The project proved to be much more challenging than expected, especially due to the difficulty in which we encountered with the new software system.
As it was she beat Jelena Dokic four and love, the score giving no idea of the difficulties in which she found herself early on.
At a noon mass on Friday at the Basilica of the Assumption, Cardinal Keeler said that Mr. Stokes had "suffered intensely because of the difficulties in which he now finds himself and which we find ourselves".
"I think all you have to do is read these vignettes in The Times about the people who have been helped and the difficulties in which they sometimes find themselves, and you just want to find a way to reach out," Mr. Carpenter said.
Given the difficulty in ascertaining which particular cells are in pre-meiosis and which are not, we further assumed that cell cycle indices remained constant throughout the PMZ for the proliferative fraction.
A primary reason for this has been the difficulty in defining which activities are part of routine medical care and which are specifically part of patient safety and infection control practices.
Previous work has described the difficulty in identifying which toxic chemicals are being generated in India via industrial processes, as well as which ones are being imported for recycling or disposal (Dutta et al. 2006).
Combined with the difficulty in remembering which key does what, it left me flustered.
Some transitions at first may seem unlikely because of the difficulty in identifying which possible functions may have been served during the intermediate stages.
Aside from the confusion that consumers may experience, the difficulty in determining which Vouvrays are truly dry is not necessarily a bad thing.
The Royal Free Trust and DeepMind have continually maintained that access to such a wide range of data is necessary for the Streams app to perform a direct patient care function, given the difficulty in predicting which patients are at risk of developing AKI.
