The difficulty arises because, upon binding, the substrate wraps around the circumference of BoNTAe constituting an unusually large substrate enzyme interface area of 4,840 Å2 (Figure 1) [17].
The difficulty arises because of the disclosed feature of the dependences between the Mellin transformed displacements and tractions at the boundaries of a thin wedge: they are linearly dependent when their Taylor's expansions in Θ0 are represented by the first terms only.
The difficulty arises because Aristotle is committed to the view that no species can occur in both the category of substance and in some other category.
The difficulty arises because there is a significant difference between ITD boundedness and Lagrange stability [2, 12 20] and the classical notion of boundedness and Lagrange stability for fractional order differential systems [4, 7].
The difficulty arises because there is a significant difference between initial time difference boundedness and Lagrange stability and the classical notion of boundedness and Lagrange stability for fractional order differential systems.
The difficulty arises because it can be questioned whether the allegedly neutral entities of a given version of neutral monism Mach's version, say are genuinely neutral or merely relabeled mental entities.
Basically, the difficulty arises because the scalar (co variance components can not be factored out from the inverse of the additive genetic covariance matrix.
The difficulty arises because typical theoretical understanding of chemical kinetics predicts a strong and nearly linear output sensitivity at low input concentrations of a signal [ 7].
The difficulty arises because it is not known, and we must replace it by its maximum-likelihood estimate, (which also minimizes X).
The difficulty arises because the condition is a result of acute respiratory failure, which is caused by an inflammatory response that is secondary to the abdominal pathology or that is due to nosocomial pneumonia [ 1, 2].
But this difficulty arises: because the proceedings are private, the basis of the decisions (and usually the decisions themselves) are never known.
