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It is possible that the co-expression of PS1dE9 changes the mixture of Aβ1-40/42 and other smaller Aβ peptide derivatives, such as Aβ38, relative to the population of Aβ derivatives produced by γ-secretase containing endogenous presenilin, and that these differences in relative levels of the different derivatives underlie our observations.
The catalytic properties (activity, specificity, and enantioselectivity) of the different derivatives have been found to be dramatically different.
Hole drift mobilities have been measured by time of flight technique in neat oligo methylphenylsilylene)s and in their molecular mixtures with the different derivatives of phenylenediamine.
Statistical analysis showed that the different derivatives had their variables influenced mainly by temperature and interaction effect between the factors time and quantity of acetylating agent.
Structure activity relationship of imidazole quinoline hybrid scaffolds revealed differential and selective toxicities exerted by the different derivatives against cancer and normal cells.
The in vitro and in vivo evaluations of the different derivatives as candidate PET radioligands for imaging Aβ plaques and neurofibrillary tangles in human brain are described in this review, along with the specific evaluation criteria by which the candidate radioligands were judged.
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Second, in the outer-stack step, three stacked models generated from the different derivative spectra space are integrated by certain weighting rules to obtain the final model.
In this case, due to the different derivative peaks, we can obtain the different optical bandgaps in only one sample and then there are different mechanical transitions.
We have several datasets for all the different derivative toxin complexes, and this observation holds true for all of them as well, in both channel molecules A and B, in the asymmetric unit.
What are the likely candidates for regulating the diversity of these different derivatives?
The three different derivatives were assessed for their ability to interact with cells (Fig. 8A) and to signal to cells (Fig. 8B).
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CEO of Professional Science Editing for Scientists @ prosciediting.com