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Although an immune response to foreign proteins can be expected and is well understood, the basis for the development of responses to therapeutic autologous proteins is the subject of some debate.
In chronic untreated infection, 70-75% of all subjects recognize the subtype B consensus SL9 sequence [55], [56], [58] and >90% recognize one or more of the common variants [61], suggesting that the development of responses against this epitope, and epitope variants, is a process that continues beyond the first years of infection, as only 6/11 recognized this epitope after the first year.
The philosophy underlying an adaptive or context-reflective approach to groundwater problems emphasizes the development of responses based on the specific constraints emerging in a local situation.
Thus, allowing the development of responses adapted to different countries' capacities without losing sight of the overall public health goals would help expand the capabilities of poorer countries.
The goal of the present study was to investigate the development of responses to these two crucial decision variables, risk and valence, from early- to mid-adolescence (aged 11 16 years).
Similarly, the development of responses to some mutations within the B∗57-restricted epitopes had been reported to be associated with the maintenance of viral suppression in HIV-1-infected B∗57+ elite suppressors [ 20, 22].
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Four input parameters were used for the development of response surface regression analysis.
The knowledge about environmental sensitivity of the marine regions to radionuclide release can be used for the development of response strategies and improvement of design-maker systems.
We found that preferred orientations of clonally related cells are similar to each other, suggesting that cell lineage is involved in the development of response selectivity of neurons in the cortex.
The evaluation of emergency, disaster and crisis management exercises supports both individual and organisational learning, facilitates the development of response capabilities, and helps to determine whether the current level of preparedness is good enough.
Studies on the extent of infection with pH1N1 are essential for pandemic severity assessment and for the development of response and vaccination strategies.
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