The development of the lesser allele intensity ratio (LAIR) algorithm that integrates the DNA index in the analysis of copy number data gives a real measure of the chromosomal alterations and allows the study of gene dosage effects in tumors.
Furthermore, we show that hepatic inflammation is of lesser importance to the development of insulin resistance compared to AT inflammation.
We hypothesize that liver inflammation comes secondary to adipose tissue inflammation and is of lesser importance to the development of metabolic inflammation and IR in diet-induced obesity.
These studies are expected to provide a new area in development of lesser polluting protective passive layer on galvanized coatings.
The main culprits are automation, cheap natural gas, and, to a lesser extent, the development of renewable energy.
Even more specifically, this means looking at the development of their form and to a lesser extent also function.
Evo-devo has been predominantly applied to the development of animals 19– 21 and, to a lesser degree, of higher plants.
We have identified the main key events that take place during the development of the olfactory system in the lesser spotted dogfish (S. canicula) and we have framed them into the context of the three developmental periods that were established on the basis of tract-tracing experiments and the expression of various immunohistochemical markers (see Fig. 1; Table 2).
This took place in the development of the Papal States and, to a lesser degree, in several theocratic churches, as well as in Calvin's ecclesiastical state in Geneva in the 16th century.
At the same time, however, increases in population, the growth of the cities, and the development of a landed class of knights and lesser nobles (vavasours), began to undermine the Ottonian system based on the support of the bishops and the great marquesses.
