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At this stage, we cannot exclude that the development of an efficacious subunit-based recombinant vaccine against PAM might require a cocktail of subunit antigens.
Thus, the development of an efficacious and safe TB vaccine is generally viewed as a critical to achieving control of the ongoing global TB pandemic.
Therefore the development of an efficacious anti-cataract drug would have a beneficial impact on both human health and healthcare costs.
Therefore, the development of an efficacious vaccine against the avian influenza virus (AIV) is desirable.
In the development of an efficacious vaccine against APP, the immunogenicities of multicomponent recombinant subunit vaccines were evaluated.
However the need for such research among a wider population of potential end-users has now become urgent because of the significant progress that has been made in the development of an efficacious product.
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Furthermore, the marked genetic diversity of HIV-1 and existence of distinct viral subtypes or clades further hinders the development of a universally efficacious HIV-1 vaccine.
The discovery of additional Brucella virulence factors thus may facilitate the development of a more efficacious, less reactogenic, acellular product that may either be used as a stand-alone vaccine or used to augment primary immunization with the existing live, attenuated platform.
Both these factors contribute to the exclusive specificity of RIT targeting viral antigens conferring the development of a highly efficacious, minimally toxic treatment modality.
Fourth, analyses of HIV informed us early on of ineffective immune responses to it [ 7, 8] and of the enormous antigenic diversity of the virus [ 9], which have been stumbling blocks in the development of a broadly efficacious vaccine.
While basic discovery and applied research are crucial for the development of a safe and efficacious HIV vaccine, it is important to continue to perform focused human clinical trials of different vaccine strategies to develop a highly effective and safe preventive HIV vaccine [31].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com