Sentence examples for the development of activating from inspiring English sources

The initial reports of this transformation described inactivation of the APC tumor-suppressor gene first, followed by the development of activating mutations in KRAS that promote tumor progression only in the presence of APC mutations.

There is need for a different and more comprehensive approach for the development of activated carbon composites used in commercial high technology sector.

Micropore volume by CO2 has been identified as a potential design parameter for the development of activated carbon fibre-phenolic resin composites for CO2 capture.

Thus, the tissue-engineered approach to the development of activated bone substitutes allows the creation of safe medical products that are effective for certain indications.

The development of Activated Sludge Models (ASM) was an important evolution in the modelling of Conventional Activated Sludge (CAS) processes and their use is now very well established.

Classically activated macrophages are antagonized by type 2 anti-inflammatory responses, which are driven by the development of alternatively activated macrophages.

Interestingly, PPARβ/δ also influenced the development of alternatively activated macrophages (M2 macrophage).

A later wave of gene expression is associated with the development of "alternatively activated" macrophages that facilitates increased intracellular replication of Ft and, ultimately, death [ 15].

In the development of atherosclerosis, activated smooth muscle cells in the medial layer of arteries migrate to the atherosclerotic fatty streaks in the intimal layer and produce an extensive extracellular matrix.

Moreover, due to greatly improved lipophilicity, these nonquaternary conjugates hold promise for the development of efficient centrally activating reactivators.

IGF-1 and its receptor have also been implicated in the development of cancer by activating pathways of cell survival and proliferation 84.