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After the featured reached the western Caribbean Sea, a new surface circulation developed, and initially, tropical cyclone forecast models anticipated the development of a significant storm in the eastern Gulf of Mexico.
For the most part, this has manifested itself in the growth of private piety and the development of a significant minority of Islamic politicians in local and national government.
The appearance in the mid-12th century of the first great epic in the Castilian tongue, Poema del Cid (The Poem of the Cid), signaled the beginning of the development of a significant vernacular literature.
The development of a significant neurologic deficit may be rapid.
In addition, Nature has inspired the development of a significant number of pharmaceutical agents.
Over the following days, ultrasounds showed abnormal findings due to the development of a significant stenosis that was confirmed by MRA.
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Virtual forums allow the definition of teaching and evaluating strategies that promote in the students the development of a conscious, significant and collaborative learning, by favouring communication and interaction among a group.
Direct intratumoural injection of cisplatin/epinepthrine injectable gel is a feasible and good tolerated method and results in the development of a statistically significant increase in necrosis in malignant liver tumours.
Therefore, diagnosis does not typically occur until the development of either a significant amount of abdominal fluid, or a pelvic mass, detected by physical examination or with radiologic evaluation [4].
Cardiovascular calcification lesions can lead to the development of a number of clinically significant complications, including myocardial ischaemia, myocardial infarction, impaired myocardial function, congestive heart failure, cardiac valve insufficiency and cardiac arrhythmias [43, 44].
A link between Myc and cancer is well established both in vivo and in vitro, and oncogenic activation of Myc has been observed to promote the development of a number of clinically significant cancers [ 25, 33].
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