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The definite effect of mTOR inhibition on bone metastatic cancers was recently explored in a collaborative review [ 51].
Unfortunately, due to the undesirable quality of included studies, the definite effect of TCM turned to be inconclusive in this review.
Since the definite effect of the vaccine on cervical cancer has yet to be established and many people do not know much about it, it would be difficult to effectively disseminate HPV vaccination at present.
Furthermore, given the well-recognized limitations on pancreatic cyst diagnosis based on clinical criteria (i.e., cyst morphology, size, cytology, lab analysis, and tumor markers), in the absence of a surgical pathology specimen confirmation, it is difficult to determine the definite effect of EUS-guided ethanol ablation.
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Although the general measures instituted were of some benefit no definite effect of any of the specific measures on the course of the disease could be demonstrated.
Although study conditions and systems differ in the aforementioned studies, a clear and definite effect of methotrexate on the prostaglandin pathway in synovium-derived cells is not apparent.
One possible motivation for assuming a deterministic relationship would be if there were firm theoretical reasoning to suggest a quantifiable and definite effect of population structure within the hierarchy; we are unaware of any such information in the current literature but suspect that further work in this area may provide clues as to what shape such a relationship may take.
After age 35, there is no definite effect of genetic factors on epilepsy.
After the treatment of 5-aza-2-dC, we could observe the definite demethylating effect of 5-aza-2-dC in 9 of 12 CRC cell lines with the exception of KM12SM, KM20 and WiDr.
The definite antitumor effect of CFCT in vivo provided a substantial foundation for the further development of new chemopreventive lead compounds from C. taii.
Therefore, all CRC lines didn't observe the definite demethylating effect of 5-aza-2-dC in our study.
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