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In volume rendering, the entire volume of the dataset is used for creating the final 3D image.

Prior to final analysis, the dataset was normalized, so that every sample had the same total counts.

The distribution of the efflux values in the final dataset is shown in Figure 1. Figure 1 Distribution of Efflux Values used for Training Prediction Models.

As a consequence, much of the final dataset is 'clickable', sending the user directly into the source dataset's website (e.g. OpenLifeData or KEGG URLs; see Fig. 5) – a user-friendly way of enabling further exploration of results.

We then tested all candidate mutations by capillary sequencing, and thus we are confident that the false-positive rate in the final dataset is effectively zero.

When the ratio in-OTU/out-OTU distances is 60%, 25%, or 1%, the global percent of missing data in the final dataset is 16, 24 and 64, respectively.

This indicates that the large number of significant FIS values in the final dataset is unlikely to be due to null alleles and instead indicates genetic structuring within a site.

The final dataset is in Additional file 1.

The final dataset is available in File S1.

A full copy of the final dataset is then sent to each site.

We used SNP genotypes to characterize the genomes of 288 NMRI mice to assess their suitability as a mapping population (the final dataset is available at http://cgd.jax.org/datasets/datasets.shtml).shtml

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