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The combined distance of feature vectors and skeletal graphs in the database provide an indirect measure of shape similarity between models.
We will also incorporate data regarding telomeric protein disease mutants to expand the database, provide more functionally relevant information and ultimately achieve comprehensive understanding of the telomere regulatory network and its role in the development and progression of diseases.
If adopted, this approach would offload basic statistical manipulations to the database, provide a platform for automated initial quality control and analysis, and result in savings in disk storage, data archiving and transfer time.
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