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The goal of the database is simple.
The interaction with the database is simple and limited to "PUT," "GET," and "DELETE" operations, which infers that more effort has to be put in the construction of the web application to manage complex querying.
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Our criterion for including an experiment in the database was simple.
In general, today the search of the number of publications and citations listed for individual scientists in the available literature databases is simple [17].
The use of administrative databases showed a high reliability in that we were able to retrieve the whole medical history and treatment pattern of each single patient; moreover, the linkage among administrative databases is simple to perform and does not require a specific epidemiological organization; thus the cost is very low.
The web interface to the database is not just a collection of simple tables showing the data, or a simple query to search by using sequence identifiers or keywords.
The database is accessible through a web service, with a simple web front end.
The database is updated periodically.
Therefore, the structure of the database was required to be simple, and the number of registration items was kept to a minimum.
There is a web interface to the database, which is simple and easy to use, while allowing for compounds to be searched by a number of different criteria.
Being able to answer the simple question, 'How many cases do we have in the database?' was not a simple task itself, which could be further complicated to the 'How many usable cases do we have in the database?' which was periodically asked by the responsible of data analysis and by the coordination team of the project.
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