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The data were completed using metabolic databases - mainly Metacyc [ 24], KEGG [ 22] -.
All simulations and model analyses were performed using NONMEM 7.1.2 facilitated with PsN 3.3.2 [ 9, 10], and statistical analyses of the data were completed using R 2.14.1 (http://www.r-project.org).org
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The responses were compiled using Excel and a descriptive analysis of the data was completed using SPSS.
Most of the data is completed using a paper based system with just over half of the district level staff being able to use a computer to consolidate data from health centre and district hospital [ 10].
The correlations of the experimental data were completed using the Wilson-HOC, NRTL-HOC and UNIQUAC-HOC models.
For repeated measures, missing data were completed using the last observation carried forward (LOCF) method.
Missing data were completed using information from the redundant markers of the contiguous assembly.
In those patients with missing values, data were completed using multiple imputation methods.
Network analysis of the microarray data was completed using the Ingenuity Pathway Analysis software [ 50].
Final analysis of the DICOM data was completed using Dolphin 3D (version 10.5, Dolphin Imaging, Chatsworth, CA, USA).
Analysis of the fMRI data was completed using statistical parametric mapping (SPM5; http://www.fil.ion.ucl.ac.uk/spm).ac.uk/spm
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