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As pointed out during peer review, we should consider at the outset whether the data is sufficient for fitting a non-linear model based on mean dose.
If the information from the data is sufficient (i.e., moderate-size expected counts and/or high true excess risks) the MIX model is able to separate the raised-risk and background areas quite well, producing considerably less smoothing of the raised-risk estimates than BYM.
Similar(58)
Malcolm L. Gefter, chairman and chief executive of Praecis, said the F.D.A. concerns appeared to be not about whether the drug, abarelix, works but whether the data were sufficient to support the claims the companies wanted to make for the drug.
"If the data was sufficient to warn their doctors, then all users of the product should have been made aware of it," he said.
Stop and write when the data are sufficient to tell a story that is complete and makes sense.
If the amount and quality of the data are sufficient, introduction of such additional parameters is valid for resolving spatially complex slip distributions.
And undoubtedly, the same data can be downloaded to more than one School of Public Health so that they can independently verify whether the data are sufficient to take a particular action.
For identifying phenotypically relevant mutations, a reasonable approach aimed at cost saving might be to use only one or two sequencing lanes, and test whether the data are sufficient to generate candidate lesions.
However, the data are sufficient to identify general trends.
The sequencing quality was considered to be appropriate and the data were sufficient for variation detection.
As such, the data are sufficient to estimate the pair-wise distances and allele frequencies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com